Porayette, P., Gallego, M.J., Kaltcheva, M.M., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S. (2009). Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells. Journal of Biological Chemistry, 284(35), 23806-23817.

Vadakkadath Meethal, S., Liu, T., Chan, H., Ginsburg, E., Wilson, A.C., Gray, D.N., Bowen, R.L., Vonderhaar, B.K. and Atwood, C.S. (2009). Identification of a regulatory loop for the synthesis of neurosteroids: A StAR-dependent mechanism involving HPG axis receptors. Journal of Neurochemistry, 110, 1014-1027.

Simon, D., Vadakkadath Meethal, S., Wilson, A.C., Gallego, M.J., Weinecke, S.L., Bruce, E., Lyons, P., Haasl, R.J., Bowen, R.L. and Atwood, C.S. (2009). Activin receptor signaling regulates prostatic epithelial cell adhesion and viability. Neoplasia, 11(4), 365-376.

Siedlak, S., Casadesus, G., Webber, K.M., Pappolla, M., Atwood, C.S., Smith, M.A. and Perry, G. (2009). Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer disease. Free Radical Research, 43(2), 156-164.

Gleason, C.E., Carlsson, C.M., Barnet, J.H., Meade, S.A., Setchell, K.D., Atwood, C.S., Johnson, S.C., Ries, M.L., Asthana, S. (2009). A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women. Age and Ageing, 38(1), 86-93.

Gallego, M.J., Porayette, P. Kaltcheva, M.M., Vadakkadath Meethal, S. and Atwood, C.S. (2009). Opioid and progesterone signaling is obligatory for early human embryogenesis. Stem Cells and Development. 18(5), 737-740.

Friedland, R.P., Tedesco, J., Wilson, A.C., Atwood, C.S., Smith, M.A., Perry, G. and Zagorski, M.G. (2008). Antibodies to potato virus Y bind the Abeta protein: Immunohistochemical and NMR studies. Journal of Biological Chemistry, 283(33), 22550-22556.

Haasl, R.J., Reza Ahmadi, M., Vadakkadath Meethal, S., Gleason, C.E., Johnson, S.C., Asthana, S., Bowen, R.L. and Atwood, C.S. (2008). A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimers disease in males carrying an apolipoprotein E e4 Allele, BMC Medical Genetics 9(1):37. online journal.

Rodrigues, M.A., Verdile, G., Foster, J.K., Hogervorst, E., Joesbury, K., Dhaliwal, S., Corder, E.H., Laws, S.M., Hone, E., Prince, R., Devine, A., Mehta, P., Beilby, J., Atwood, C.S. and Martins, R.N. (2008). Gonadotropins and Cognition in Older Women. Journal of Alzheimers Disease, 13(3):267-274.

Wilson, A.C., Clemente, L., Liu, T., Bowen, R.L., Vadakkadath Meethal, S. and Atwood, C.S. (2008). Reproductive hormones regulate the selective permeability of the blood-brain barrier. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1782(6):401-7.

Carlsson, C.M., Gleason, C.E., Hess, T.M., Moreland, K.A., Blazel, H.M., Koscik, R.L., Schreiber, N.T.N., Johnson, S.C., Atwood, C.S., Puglielli, L., Hermann, B.P., McBride, P.E., Stein, J.H., Sager, M.A. and Asthana, S. (2008). Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimers disease. Journal of Alzheimers Disease, 13(2):187-97.

Atwood, C.S. and Bowen, R.L. (2008). A multi-hit endocrine model of intrinsic adult-onset asthma. Ageing Research Reviews, 7(2):114-125.

Gonzalez-Cuyar, L.F., Perry, G., Miyajima, H., Atwood, C.S., Riveros-Angel, M., Lyons, P.F., Siedlak, S.L., Smith, M.A., Castellani, R.J. (2008). Redox active iron accumulation in aceruloplasminemia. Neuropathology. 28(5), 466-471.

Porayette, P., Gallego, M.J., Kaltcheva, M.M., Vadakkadath Meethal, S. and Atwood, C.S. (2007). Amyloid-b precursor protein expression and modulation in human embryonic stem cells: A novel role for human chorionic gonadotropin. Biochemical and Biophysical Research Communications, 364(3), 522-527.

Bishop, G.M., Smith, M.A., LaManna, J.C., Wilson, A.C., Perry, G., Atwood, C.S. (2007). Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Report 12(6), 257-266.

Chan, H.W., Liu, T., Verdile, G., Bishop, G.M., Haasl, R.J., Smith, M.A., Perry, G., Martins, R.N. and Atwood, C.S. (2008). Copper induces apoptosis of neuroblastoma cells via post-translational regulation of the expression of Bcl-2-family proteins and the txJ mouse is a better model of hepatic than brain Cu toxicity. International Journal of Clinical and Experimental Medicine, 1, 76-86.

Trivedi, M.A., Schmitz, T.W., Ries, M.L., Hess, T.M., Fitzgerald, M.E., Atwood, C.S., Rowley, H.A., Asthana, S., Sager, M.A. and Johnson, S.C. (2008). fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: Risk factors for Alzheimer's disease. Neuropsychologia. 46(6):1667-1678.

Porayette, P., Gallego, M.J., Kaltcheva, M.M., Vadakkadath Meethal, S. and Atwood, C.S. (2007). Amyloid-beta precursor protein expression and modulation in human embryonic stem cells: A novel role for human chorionic gonadotropin. Biochemical and Biophysical Research Communications, 364(3), 522-527.

Bishop, G.M., Smith, M.A., LaManna, J.C., Wilson, A.C., Perry, G., Atwood, C.S. (2007). Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Report [in press].

Liu, T., Wimalasena, J., Bowen, R.L. and Atwood, C.S. (2007). Luteinizing hormone receptor mediates neuronal pregnenolone production via upregulation of steroidogenic acute regulatory protein expression. Journal of Neurochemistry, 100(5):1329-1339.

Wung, J.K., Perry, G., Kowalski, A.., Harris, P.L.R., Bishop, G.M., Trivedi, M.A., Johnson, S.C., Smith, M.A., Denhardt, D.T. and Atwood, C.S. (2007) Increased expression of the remodeling-associated factor osteopontin in pyramidal neurons of the Alzheimer’s disease brain. Current Alzheimer Research, 4(1):67-72.

Wilson, A.C., Salamat, S., Haasl, R.J., Roche, K.M., Karande, A., Vadakkadath Meethal, S., Terasawa, E., Bowen, R.L. and Atwood, C.S. (2006). Human extra-pituitary neurons possess GnRH I receptors that respond to GnRH by expressing luteinizing hormone. Journal of Endocrinology, 191, 651-665.

Vadakkadath Meethal, S., Gallego, M., Haasl, R.J., Petras, S.J., Sgro, J.Y., Bowen, R.L. and Atwood, C.S. (2006). Identification of a gonadotropin-releasing hormone receptor orhtologue in Caenorhabditis elegans. BMC Evolutionary Biology, 6:103.

Atwood, C.S. and Bowen, R.L. (2007). Metabolic clues regarding the enhanced performance of elite endurance athletes from orchiectomy-induced hormonal changes. Medical Hypotheses, 68(4):735-749

Casadesus, G., Webber, K.M., Atwood, C.S., Pappolla, M.A., Perry, G., Bowen, R.L. and Smith, M.A. (2006). Luteinizing hormone modulates cognition and amyloid-ß deposition in Alzheimer APP transgenic mice. Biochemica Biophyica. Acta 1762(4), 447-452.

Cui, Z., Lockman, P.R., Atwood, C.S., Hsu, C.-H., Gupte, A., Allen, D.D. and Mumper, R.J. (2005). Novel D-penicillamine carrying nanoparticles for potential treatment of ß-amyloid accumulation in brain. European Journal of Pharmaceutics and Biopharmaceutics, 59, 263-272.

Huang, X., Atwood, C.S., Moir, R.D., Hartshorn, M.A., Tanzi, R.E. and Bush, A.I. (2004). Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides. Journal of Biological Inorganic Chemistry, 9, 954-960.

Bowen, R.L. and Atwood, C.S. (2004). Living and Dying for Sex: A theory of aging based on the modulation of cell cycle signaling by reproductive hormones. Gerontology 50(5):265-290.

Zhu, X., Wang, Y., Ogawa, O., Lee, H.G., Raina, A.K., Siedlak, S.L., Harris, P.L., Fujioka, H., Shimohama, S., Tabaton, M., Atwood, C.S., Petersen, R.B., Perry, G., Smith, M.A. (2004). Neuroprotective properties of Bcl-w in Alzheimer disease. J. Neurochem. 89, 1233-1240.

Zhu, X., McShea, A., Harris, P.L.R., Raina, A.K., Castellani, R.J., Funk, J.O., Shah, S., Atwood, C.S., Bowen, R., Bowser, R., Morelli, L., Perry , G. and Smith , M.A. (2004). Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer’s disease. Journal of Neuroscience Research 75, 698–703.

Bowen, R.L., Verdile, G., Liu, T., Perry, G., Smith, M.A., Martins, R.N. and Atwood, C.S. (2004). Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-ß protein precursor and amyloid-ß deposition. Journal of Biological Chemistry 279(19), 20539-45.

Liu, T., Perry, G., Chan, H.W., Verdile, G., Martins, R.N., Smith, M.A. and Atwood, C.S. (2004). Amyloid-ß-induced toxicity of primary neurons is dependent upon differentiation associated increases in tau and cyclin-dependent kinase 5. Journal of Neurochemistry, 88(3), 554-563.

Atwood, C.S., Perry, G., Zeng, H., Kato, Y., Jones, W.D., Ling, K.Q., Huang, X., Moir, R.D., Wang, D., Sayre, L.M., Smith M.A., Chen, S.G. and Bush, A.I. (2004). Copper mediated crosslinking reactions of Alzheimer's amyloid-ß. Biochemistry, 43(2), 560-568.

Dong, J., Atwood, C.S., Anderson, V.E., Siedlak, S.L., Smith, M.A., Perry, G. and Carey, P.R. (2003). Metal binding and oxidation of amyloid-ß within isolated senile plaque cores: Raman microscopic evidence. Biochemistry, 42(10), 2768-2773.

Veurink, G., Liu, D., Taddei, K., Perry, G., Smith, M.A., Robertson, T.A., Hone, E., Groth, D.M., Atwood, C.S. and Martins, R.N. (2003). Reduction of inclusion body pathology in Apo-E-deficient mice fed a combination of antioxidants. Free Radicals in Biology and Medicine, 34(8), 1070-1077.

Perry, G., Taddeo, M.A., Petersen, R.B., Castellani, R.J., Harris, P.L.R., Sidlak, S.L., Cash, A.D., Liu, Q, Nunomura, A., Atwood, C.S., Smith, M.A. (2003). Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer's disease. Biometals, 16, 77-81.

Bowen, R.L., Smith, M.A., Harris, P.L.R., Kubat, Z., Martins RN, Castellani, R.J., Perry, G. and Atwood, C.S. (2002). Elevated luteinizing hormone expression colocalizes with neurofibrillary tangles in Alzheimer disease. Journal of Neuroscience Research, 70(3), 514-518.

Zhu, X., Castellani, R.J., Takeda, A., Nunomura, A., Atwood, C.S., Perry, G., Smith, M.A. (2001). Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mechanisms of Ageing Development, 123, 39-46.

Nunomura, A., Perry, G., Aliev, G., Hirai, K., Takeda, A., Balraj, E.K., Jones, P.K., Ghanbari, H., Wataya, T., Shimohama, S., Chiba, S., Atwood, C.S., Petersen, R.B., Smith, M.A. (2001). Oxidative damage is the earliest event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology, 60, 759-767.

Fonte, J., Miklossy, J., Atwood, C.S. and Martins, R. (2001). Alzheimer’s disease neuropathology is positively correlated with increased beta amyloid levels: Resolubilization with transition metal chelators. Journal of Alzheimer Disease 3, 209-219.

Castellani, R.J., Harris, P.L., Sayre, L.M., Fujii, J., Taniguchi, N., Vitek, M.P., Founds, H., Atwood, C.S., Perry, G., Smith, M.A. (2001) Active glycation in neurofibrillary pathology of Alzheimer disease: N(varepsilon)-(Carboxymethyl) lysine and hexitol-lysine. Free Radicals in Biology and Medicine 31, 175-180.

Cherny, R.A.*, Atwood, C.S*., Xilinas, M.E., Gray, D.N., Jones, W.D., McLean, C.A. Barnham, K.J., Volitakis, I., Fraser, F.W., Kim, Y.-S., Huang, X., Goldstein, L.E., Moir, R.D., Lim, J.T., Beyreuther, K.T., Zheng, H., Tanzi , R.E., Masters, C.L. and Bush, A.I. (2001). Treatment of a copper-zinc chelator markedly and rapidly inhibits ß-Amyloid accumulation in Alzheimer disease transgenic mice. Neuron 30, 665-676. * First two authors contributed equally.

Rottkamp, C.A., Raina, A.K., Zhu, X., Gaier, E., Bush, A.I., Atwood, C.S., Chevion, M., Perry, G., Smith, M.A. (2001). Redox-active iron mediates amyloid-beta toxicity. Free Radicals in Biology and Medicine 30, 447-450.

Atwood, C.S., Scarpa, R.C., Huang, X., Moir, R.D., Jones, W.D., Fairlie, D.P., Tanzi, R.E. and Bush, A.I. (2000). Characterization of copper interactions with Alzheimer amyloid beta peptides: Identification of an attomolar-affinity copper binding site on amyloid beta1-42. Journal of Neurochemistry, 75, 1219-1233.

Hirai, K., Aliev, G., Nunomura, A., Russell, R.L., Atwood, C.S., Johnson, A.B., Kress, Y.,Vinters, H.V., Tabaton, M., Cash, A., Siedlak, S.L., Jones, P.K., Petersen, R.B., Perry, G. and Smith, M.A. (2001). Mitochondrial DNA turnover is decreased in oxidatively stressed pyramidal neurons of the Alzheimer’s disease brain . Journal of Neuroscience21, 3017-3023.

Atwood, C.S., Hovey, R., Glover, J.P., Chepko, G., Ginsburg, E., Robison, Jr., W.G. and Vonderhaar, B.K. (2000). Progesterone induces ductal side-branching of the ductal epithelium in the mammary glands of peripubertal mice. Journal of Endocrinology 167, 39-52.

Cuajungco, M.P., Goldstein, L.E., Nunomura, A., Smith, M.A., Lim, J.T., Atwood, C.S., Huang, X., Farrag, Y.W., Perry, G. and Bush, A.I. (2000). Evidence that the ß-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aß by zinc. Journal of Biological Chemistry, 275, 19439-19442.

Goldstein, L.E., Hartshorn, M., Leopold, M., Huang, X., Atwood, C.S., Saunders, A.J., Lim, J., Scarpa, R.C., Chylack, L.T. Jr., Bowden, E.F., Tanzi, R.E. & Bush, A.I. (2000). 3-Hydroxykynurenine and 3-Hydroxyanthranilic acid generate hydrogen peroxide and promote crystallin crosslinking by metal ion reduction. Biochemistry, 39(24), 7266-7275.

Atwood, C.S., Huang, X., Khatri, A., Scarpa, R.C., Kim, Y.-S., Moir, R.D., Tanzi, R.E., Roher, A.E., and Bush, A.I. (2000). Copper catalyzed oxidation of Alzheimer Aß. Cellular and Molecular Biology 46(3), 777-783.

Huang, X., Atwood, C.S., Hartshorn, M.A., Multhaup, G., Goldstein, L.E., Scarpa, R.C., Cuajungco, M.P., Gray, D.N., Lim, J., Moir, R.D., Tanzi, R.E. and Bush, A.I. (1999). The Aß peptide of Alzheimer’s disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 38, 7609-7616.

Huang, X., Cuajungco, M.P., Atwood, C.S., Hartshorn, M.A., Tyndall, J., Hanson, G.R., Stokes, K.C., Multhaup, G., Goldstein, L.E., Scarpa, R.C., Saunders, A.J., Lim, J., Moir, R.D., Glabe, C., Bowden, E.F., Masters, C.L., Fairlie, D.P., Tanzi, R.E. and Bush, A.I. (1999). Alzheimer Aß interaction with Cu(II) induces neurotoxicity, radicalization, metal reduction and hydrogen peroxide formation. Journal of Biological Chemistry 274, 37111-37116.

Cherny, R.A., Legg, J.T., McLean, C.A., Fairlie, D.P., Huang, X., Atwood, C.S., Tanzi, R.E., Masters, C.L. and Bush, A.I. (1999). Aqueous dissolution of Alzheimer’s disease Aß amyloid deposits by biometal depletion. Journal of Biological Chemistry 274, 23223-23228.

Moir, R.D., Atwood, C.S., Bush, A.I., Romano, D.M., Huang, X., Smith, J. and Tanzi, R.E. (1999). Differential effects of apolipoprotein E isoforms on metal-induced aggregation of Aß under physiological conditions. Biochemistry 38, 4595-4603.

Chan, C.-W., Dharmarajan, A., Atwood, C.S., Huang, X., Tanzi, R.E., Bush, A.I., and Martins, R.N. (1999). Anti-apoptotic action of Alzheimer Aß. Alzheimer’s Reports 2(2), 1-6.

Atwood, C.S., Huang, X., Moir, R.D., Bacarra, N.M., Romano, D., Tanzi, R.E. and Bush, A.I. (1998). Dramatic aggregation of Alzheimer Aß by Cu(II) is induced by conditions representing physiological acidosis. Journal of Biological Chemistry 273, 12817-12826.

Huang, X., Atwood, C.S., Moir, R.D., Hartshorn, M.A., Vonsattel, J-P., Tanzi, R.E. and Bush, A.I. (1997). Zinc-induced Alzheimer’s Aß1-40 aggregation is mediated by conformational factors. Journal of Biological Chemistry 272, 26464-26470.

Pluske, J.R., Thompson, M.J., Atwood, C.S., Bird, P.H., Williams, I.H & Hartmann, P.E. (1996). Maintenance of villus height and crypt depth, and enhancement of disaccharide digestion and monosaccharide adsorption, in piglets fed on cows’ whole milk after weaning. British Journal of Nutrition 76, 409-422.

Toner, M.S., King, R.H., Dunshea, F.R., Dove, H. and Atwood, C.S. (1996). The effect of exogenous somatotrophin on lactation performance of first-litter sows. Journal of Animal Science 74, 167-172.

Atwood, C.S., Ikeda, M and Vonderhaar, B.K. (1995). Involution of mouse mammary glands in whole organ culture: a model for studying programmed cell death. Biochemical and Biophysical Research Communications 207(2), 860-867.

Bird, P.H., Atwood, C.S. and Hartmann, P.E. (1995). The responses of blood galactose to oral doses of lactose, galactose plus glucose and milk to piglets. British Journal of Nutrition 73, 753-761.

Atwood, C.S. & Hartmann, P.E. (1995). The assessment of mammary gland metabolism in the sow: Cellular metabolites in the mammary secretion and plasma following weaning. Journal of Dairy Research 62(2), 221-236.

Atwood, C.S., Toussaint, J.K. & Hartmann, P.E. (1995). The assessment of mammary gland metabolism in the sow: Cellular metabolites in the mammary secretion and plasma during lactogenesis II. Journal of Dairy Research 62(2), 207-220.

Atwood, C.S. & Hartmann, P.E. (1995). The assessment of mammary gland metabolism in the sow: The development of methods for the measurement of cellular metabolites in milk and colostrum. Journal of Dairy Research 62(2), 189-206.

Atwood, C.S. (1993). The measurement of fat, protein, lactose and cellular metabolites in milk for the assessment of lactocyte function during the lactation cycle of the sow. Ph.D. Thesis. The University of Western Australia.

Atwood, C.S. and Hartmann, P.E. (1993). The concentration of fat, protein and lactose in sows' colostrum from sucked and unsucked glands during lactogenesis II. Australian Journal of Agricultural Research 44, 1457-1465.

King, R.H., Toner, M.S., Dove, H., Atwood, C.S. and Brown, W.G. (1993). The response of first-litter sows to dietary protein level during lactation. Journal of Animal Science 71, 2457-2463.

Atwood, C.S. and Hartmann, P.E. (1992). Collection of fore and hind milk from the sow and the changes in milk composition during suckling. Journal of Dairy Research 59(3), 287-298.

Atwood, C.S., Toussaint, J.K. and Hartmann, P.E. (1991). The concentration of cellular metabolites in sows' milk change during lactogenesis. In: Manipulating Pig Production III. Proceedings of the Biennial Conference of the Australasian Pig Science Association (A.P.S.A.), p 74. Ed E.S. Batterham (Australasian Pig Science Association, Attwood, Victoria, Australia).

Atwood, C.S., James, I.R., Kiel, U., Roberts, N.K. and Hartmann, P.E. (1991). Circadian changes in salivary constituents and conductivity in women and men. Chronobiologia 18(4), 125-140.

Guppy, M., Bradshaw, S.D., Ferguson, B., Hansen, I.A. and Atwood, C.S. (1987). Metabolism in lizards: low lactate turnover and advantages of heterothermy. The American Physiological Society 253 (Regulatory Integrative Comparative Physiology 22), R77-82.